The Bad News – It has been reported the there are dozens of medications that can trigger systemic lupus erythematosus (SLE). The drugs most lightly to cause “drug-induced lupus” –
Hydralazine for blood pressure
Quinidine and Procainamide used for abnormal heart rhythms
Phenytoin used for epilepsy
Isoniazid used for tuberculois
D-penicillamine used for rheumatoid arthritis
The Good News – These drugs are known to stimulate the immune system and cause SLE. Usually drug-induced SLE accounts for about 5% and generally the symptoms subside when you stop taking the medications.